The crystal structure of the monoamine oxidase B (MAO-B) enzyme with the anti-diabetic drug rosiglitazone co-crystalized shows the molecular interaction between the drug and the protein. This information can be used to rationally design novel compounds to be used in a variety of neurological diseases including Parkinson’s disease.

Department of Pharmaceutical & Pharmacological Sciences Program

Research programs allow faculty members at the WVU School of Pharmacy to help educate and train future scientists and researchers.

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The Department of Pharmaceutical and Pharmacological Sciences is dedicated to improving human health by educating pharmacy and graduate students in pharmaceutical and pharmacological sciences and by conducting and promoting research for the discovery, design, action, and development of therapeutic agents.